Desperate for new lives, a bumbling bounty hunter and a notorious criminal team up in hopes of making enough money to start over on Earth. After both accepting a strange job offer to become Exterminators, the duo is thrust into the underground world of slaying Interlopers, biosynthetic androids disguised as human beings. As they track down the origin of an Interloper called the Conqueror Worm, they begin to uncover a dark megacorporation conspiracy capable of not only destroying their dreams, but also destroying the very fabric of reality itself.